Ethylparaben

Ethylparaben^[1]

IUPAC name Ethyl 4-hydroxybenzoate
Other names Ethyl paraben; Ethyl parahydroxybenzoate; Ethyl para-hydroxybenzoate; Ethyl p-hydroxybenzoate; 4-Hydroxybenzoic acid ethyl ester
Identifiers
CAS number	120-47-8^Y
PubChem	8434
ChemSpider	13846749^Y
UNII	14255EXE39^Y
KEGG	D01647^Y
MeSH	ethyl-p-hydroxybenzoate
ChEMBL	CHEMBL15841^Y
Jmol-3D images	Image 1
SMILES O=C(OCC)c1ccc(O)cc1
InChI InChI=1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3^Y Key: NUVBSKCKDOMJSU-UHFFFAOYSA-N^Y InChI=1/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3 Key: NUVBSKCKDOMJSU-UHFFFAOYAQ
Properties
Molecular formula	C₉H₁₀O₃
Molar mass	166.17 g mol⁻¹
Melting point	115–118 °C
Boiling point	297–298 °C
Hazards
Flash point	248 °C
Related compounds
Related compounds	Paraben Butylparaben Methylparaben Propylparaben
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Ethylparaben (ethyl para-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid. Its formula is HO-C₆H₄-CO-O-CH₂CH₃. It is a member of the class of compounds known as parabens.

It is used as an antifungal preservative. As a food additive, it has E number E214.

Sodium ethyl para-hydroxybenzoate, the sodium salt of ethylparaben, has the same uses and is given the E number E215.

References

^ Ethyl paraben, thegoodscentscompany.com

Antifungals (D01 and J02)

Wall/
membrane

Ergosterol
inhibitors

Azoles
(lanosterol 14
alpha-demethylase inhibitors)

Imidazoles	topical: Bifonazole, Butoconazole, Clomidazole, Clotrimazole^#, Croconazole, Econazole, Fenticonazole, Ketoconazole, Isoconazole, Miconazole^#, Neticonazole, Omoconazole, Oxiconazole, Sertaconazole, Sulconazole, Tioconazole

Triazoles	topical: (Fluconazole^#, Fosfluconazole, Terconazole) systemic: (Fluconazole, Hexaconazole, Isavuconazole^†, Itraconazole, Posaconazole, Voriconazole) unknown: (Albaconazole)

Thiazoles	topical: (Abafungin)

Polyene antimycotics
(ergosterol binding)

topical: (Hamycin, Natamycin, Nystatin^#)
systemic: (Amphotericin B^#, Hamycin)

Allylamines
(squalene monooxygenase
inhibitors)

topical: (Amorolfine, Butenafine, Naftifine, Terbinafine)
systemic: (Terbinafine)

β-glucan synthase
inhibitors

echinocandins (Anidulafungin, Caspofungin, Micafungin)

Intracellular

Pyrimidine analogues/ Thymidylate synthase inhibitors	Flucytosine^#

Mitotic inhibitors	Griseofulvin^#

Others

Bromochlorosalicylanilide • Methylrosaniline • Tribromometacresol • Undecylenic acid • Polynoxylin • Chlorophetanol • Chlorphenesin • Ticlatone • Sulbentine • Ethyl hydroxybenzoate • Haloprogin • Salicylic acid • Selenium sulfide^# • Ciclopirox • Amorolfine • Dimazole • Tolnaftate • Tolciclate • Sodium thiosulfate^# • Whitfield's ointment^# • Potassium iodide^# • Taurolidine

Tea tree oil • citronella oil • lemon grass • orange oil • patchouli • lemon myrtle

PCP: Pentamidine • Dapsone • Atovaquone

^#WHO-EM. ^‡Withdrawn from market. Clinical trials: ^†Phase III. ^§Never to phase III

M: MYC

fung, clas

fung

drug (fung)